VIB Nanobody Core is engaged in the planning and execution of various projects which cover a broad spectrum of subjects, ranging from developing research tools to identification and optimization of leads for diagnostic and therapeutic purposes in the field of cancer, inflammatory and infectious diseases, neurodegenerative diseases, etc. In addition to continuous improvement on the existing technology in order to further streamline the generation, identification and engineering of Nanobodies, the VIB Nanobody Core has been and is involved in developing novel Nanobody-based technology platforms. Examples of such technologies developed by VIB Nanobody Core are Nanobody-based serum half-life extension of therapeutics, viral load quantification by Nanobodies, Nanobody-based ChIP-chip, and Nanobody-based target discovery platform aiming at the discovery of novel diagnostic and therapeutic targets.